Guidelines, guides and protocols for deprescribing specific drug classes.

Evidence-based deprescribing guidelines with algorithms and other implementation tools

Cholinesterase Inhibitors (ChEIs) and Memantine 

Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine.

Resources and reports:


Clinical Practice Guideline for Deprescribing Opioid Analgesics aims to provide evidence-based recommendations on when and how to deprescribe opioids for adults prescribed opioids for pain in primary care settings.

Resources and reports:


 Visit for guidelines and other resources for:

  • Proton Pump Inhibitors
  • Antihyperglycemics
  • Antipsychotics
  • Benzodiazepine Receptor Antagonist

Deprescribing guides for use in hospital

Guidance for clinicians to support decisions on whether and how to deprescribe specific drug classes. Complementary resources for clinicians to give consumers to support implementation of deprescribing decisions. The deprescribing resources have been developed by a translational research project team led by Prof Sarah Hilmer, for clinicians to support deprescribing in older hospital patients.

For more information on the development of these resources see Jokanovic et al 2019, and Duong et al 2021.


Primary Health Tasmania deprescribing guides 

Primary Health Tasmania has deprescribing guides for medications, deprescribing fact sheets videos and other resources for consumers and healthcare professionals. Primary Health Tasmania is an organisation under the Australian Government’s Primary Health Networks Program. Their deprescribing resources have been created and revised by the Deprescribing Reference Group, geriatrician Dr David Dunbabin, GP Dr Amanda Lo and pharmacist Dr Peter Tenni.


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